Isaac Guerendo Takes It to the House to Cap 64-Yard Drive

Watch the top highlights of San Francisco 49ers tight end George Kittle from the 2024 NFL season.

Watch highlights of San Francisco 49ers quarterback Brock Purdy from the 2024 NFL season.

Watch highlights of San Francisco 49ers 2025 Pro Bowlers TE George Kittle, LB Fred Warner, DL Nick Bosa and FB Kyle Juszczyk from the 2024 NFL Season.

Watch San Francisco 49ers quarterback Joshua Dobbs' best plays from his three touchdown game vs. the Arizona Cardinals during Week 18 of the 2024 NFL season.

San Francisco 49ers FB Kyle Juszczyk hauled in a touchdown during the team's Week 18 matchup against the Cardinals.

San Francisco 49ers WR Ricky Pearsall caught a touchdown pass from QB Joshua Dobbs during the team's Week 18 matchup against the Cardinals.

San Francisco 49ers quarterback Joshua Dobbs pushed through the Cardinal's defense on a QB sneak to close the gap.

San Francisco 49ers QB Joshua Dobbs connected with rookie WR Ricky Pearsall on a 30-yard pass during the team's Week 18 matchup against the Cardinals.

The San Francisco 49ers K Jake Moody punched in a 51-yard field goal in the last game of the 2024 season against the Cardinals.

Watch the San Francisco 49ers top highlights vs. the Detroit Lions in the Week 17 contest.

Check out San Francisco 49ers tight end George Kittle's best catches from his 112-yard game vs. the Detroit Lions during Week 17 of the 2024 NFL season.

View the best plays from San Francisco 49ers quarterback Brock Purdy's four touchdown, 389-yard game vs. the Detroit Lions in Week 17 during the 2024 NFL season.

View the best plays from San Francisco 49ers rookie WR Ricky Pearsall's 141-yard game vs. the Detroit Lions during Week 17 of the 2024 NFL season.

San Francisco 49ers DL Nick Bosa sacked Detroit Lions QB Jared Goff for a loss of 13 yards in the team's Week 17 matchup.

San Francisco 49ers QB Brock Purdy connected with WR Deebo Samuel Sr. for a touchdown on "MNF."

San Francisco 49ers QB Brock Purdy scored a touchdown on "MNF" against the Detroit Lions in the team's Week 17 matchup.

San Francisco 49ers QB Brock Purdy threw a dart to WR Ricky Pearsall on "MNF" against the Detroit Lions.

San Francisco 49ers WR Ricky Pearsall secured a one-handed catch in the team's Week 17 matchup against the Detroit Lions.

San Francisco 49ers TE George Kittle secured his 1,000-yard mark on the season with a 20-yard reception vs. the Lions.

San Francisco 49ers FB Kyle Juszczyk slipped past Lions defenders for a 9-yard touchdown on "MNF."

San Francisco 49ers DL Jordan Elliott blocked Detroit Lions K Jake Bates's point after a touchdown attempt in the team's Week 17 matchup.

San Francisco 49ers QB Brock Purdy threw a dart to WR Ricky Pearsall for a touchdown during "MNF" against the Detroit Lions.

San Francisco 49ers TE Eric Saubert scored a touchdown during the team's Week 16 matchup against the Miami Dolphins.

San Francisco 49ers QB Brock Purdy connected with TE George Kittle for a crucial 28-yard gain in the team's Week 16 matchup against the Dolphins.

San Francisco 49ers tight end George Kittle turned on the jets for a 25-yard catch and run during the team's Week 16 matchup against the Miami Dolphins.