Isaac Guerendo's Takes Off for a 93-Yard Kick Return

San Francisco 49ers QB Brock Purdy stepped up in the pocket and delivered a 16-yard strike to rookie WR Ricky Pearsall against the Los Angeles Rams.

San Francisco 49ers kicker Jake Moody made a 53-yard field goal against the Los Angeles Rams.

San Francisco 49ers QB Brock Purdy connected with TE George Kittle on 'TNF' against the Los Angeles Rams.

Watch San Francisco 49ers tight end George Kittle's Week 14 highlights as he caught six passes for 151 yards against the Chicago Bears.

Watch San Francisco 49ers quarterback Brock Purdy's best plays from his two-touchdown game against the Chicago Bears in Week 14.

Watch highlights from San Francisco 49ers wide receiver Jauan Jennings in Week 14 as he caught seven passes for 90 yards and a pair of touchdowns against the Chicago Bears.

Watch the San Francisco 49ers top highlights vs. the Chicago Bears in the Week 14 contest.

San Francisco 49ers RB Patrick Taylor Jr. pushed in for the score in the team's Week 14 matchup against the Bears.

San Francisco 49ers DL Evan Anderson recovered a fumble by Chicago Bears QB Caleb Williams.

San Francisco 49ers rookie RB Isaac Guerendo punched in a touchdown in the team's Week 14 matchup against the Chicago Bears.

San Francisco 49ers QB Brock Purdy connected a 16-yard touchdown pass to Jauan Jennings in the team's Week 14 matchup against the Bears.

San Francisco 49ers rookie RB Isaac Guerendo scored a one-yard touchdown in the team's Week 14 matchup against the Chicago Bears.

San Francisco 49ers TE George Kittle slips through a crease for a 33-yard burst up the sideline.

San Francisco 49ers QB Brock Purdy connected a touchdown pass to WR Jauan Jennings in the team's Week 14 matchup against the Bears.

San Francisco 49ers RB Isaac Guerendo sped past the Buffalo Bills defense for a touchdown on "SNF".

San Francisco 49ers WR Deebo Samuel Sr. has room to roam on a 60-yard kick return in the team's Week 13 matchup against the Buffalo Bills.

San Francisco 49ers RB Jordan Mason zipped through Bills defenders for a 27-yard run in the team's Week 13 matchup against the Buffalo Bills.

San Francisco 49ers RB Christian McCaffrey powers through for a 19-yard run against the team's Week 13 matchup against the Buffalo Bills.

Check out the top 10 catches from San Francisco 49ers tight end George Kittle from his eight year career, so far.

Watch the San Francisco 49ers top highlights from TE George Kittle, WR Deebo Samuel Sr., DL Leonard Floyd and more vs. the Green Bay Packers in Week 12.

San Francisco 49ers' linebacker Leonard Floyd bags his second sack of Green Bay Packers' quarterback Jordan Love, and while he doesn't force a turnover he does the Packers to punt.

San Francisco 49ers TE George Kittle makes a back-hip catch to advance the 49ers into Green Bay Packers territory.

San Francisco 49ers DL Leonard Floyd sacked the Green Bay Packers QB Jordan Love.

San Francisco 49ers RB Jordan Mason takes the football for a 16-yard gain in the team's Week 12 matchup against the Packers.

San Francisco 49ers WR Deebo Samuel caught a trick-play pass from QB Brandon Allen in the team's Week 12 matchup against the Green Bay Packers.