Charley Casserly's Top 5 Defensive End Prospects

San Francisco 49ers fourth-round draft pick, Louisville running back Isaac Guerendo, runs the 40-yard dash at the 2024 NFL Scouting Combine.

San Francisco 49ers third-round draft pick, Kansas offensive lineman Dominick Puni, runs the 40-yard dash at the 2024 NFL Scouting Combine.

San Francisco 49ers fourth-round draft pick, Arizona wide receiver Jacob Cowing, runs the 40-yard dash at the 2024 NFL Scouting Combine.

San Francisco 49ers second-round draft pick, Florida State cornerback Renardo Green, runs the 40-yard dash at the 2024 NFL Scouting Combine.

San Francisco 49ers first-round draft pick, Florida wide receiver Ricky Pearsall, goes through drills at the 2024 NFL Scouting Combine.

San Francisco 49ers first-round draft pick, Ohio State defensive lineman Nick Bosa, runs through drills at the 2019 NFL Scouting Combine.

San Francisco 49ers third-round draft pick, BYU linebacker Fred Warner, runs through drills at the 2018 NFL Scouting Combine.

San Francisco 49ers seventh-round draft pick, Iowa State quarterback Brock Purdy, goes through drills at the 2022 NFL Scouting Combine.

San Francisco 49ers fifth-round draft pick, Iowa tight end George Kittle, runs through drills at the 2017 NFL Scouting Combine.

NFL commissioner Roger Goodell spoke at the ceremonial transition of Super Bowl host cities following Super Bowl LIX in New Orleans.

San Francisco 49ers tight end George Kittle presents his speech after winning the 2024 USAA Salute to Service Award at the 14th annual NFL Honors.

San Francisco 49ers tight end George Kittle shares appreciation for military service members after receiving the 2024 Salute to Service Award at the NFL Honors Red Carpet.

Here is the NFL's list of everything you need to know when the San Francisco 49ers play the Green Bay Packers in Week 12 of the 2024 NFL season.

Here is the NFL's list of everything you need to know when the San Francisco 49ers play the Seattle Seahawks in Week 11 of the 2024 NFL season.

Here is the NFL's list of everything you need to know when the San Francisco 49ers play the Tampa Bay Buccaneers in Week 10 of the 2024 NFL season.

San Francisco 49ers linebacker Fred Warner spoke about the 49ers "Thursday Night Football" victory over the Seattle Seahawks ahead of their Super Bowl rematch vs. the Kansas City Chiefs.

Here is the NFL's list of everything you need to know when the San Francisco 49ers play the Seattle Seahawks in Week 6 of the 2024 NFL season.

Here is the NFL's list of everything you need to know when the San Francisco 49ers play the Arizona Cardinals in Week 5 of the 2024 NFL season.

Here is the NFL's list of everything you need to know when the San Francisco 49ers play the New England Patriots in Week 4 of the 2024 NFL season.

Take a look at some of the San Francisco 49ers best plays versus NFC West opponents of all time.

NFL Network's "Good Morning Football" crew recapped the biggest takeaways from the San Francisco 49ers "Monday Night Football" win vs. the New York Jets in Week 1.

Listen to Hall of Fame inductee and former San Francisco 49ers linebacker Patrick Willis' full speech at the 2024 Pro Football Hall of Fame enshrinement in Canton, Ohio.

San Francisco 49ers linebacker Fred Warner joined "Back Together Weekend" on NFL Network after practice at the SAP Performance Facility to discuss the team's new defensive coaching staff, fatherhood and becoming "the best version of himself."

San Francisco 49ers running back Christian McCaffrey joined NFL Network's "The Insiders" for an exclusive interview after being named the "Madden NFL 25" cover athlete.

In a segment on 'Schedule Release '24' breaking down the NFC West, NFL Network's Cynthia Frelund goes through her win total projections for the Los Angeles Rams, San Francisco 49ers, Seattle Seahawks and Arizona Cardinals.