History: 49ers at Giants
- The 49ers are 20-21 overall against the Giants, including an 8-11 record on the road.
- San Francisco travels to MetLife Stadium to take on the Giants for the first time since 2015. The two teams have split each of the past two contests played at MetLife, with the last 49ers win coming in a 16-10 victory in 2014.
- The 49ers and Giants have alternated wins in each of the previous five matchups.
Players and Coaches to Know:
49ers
- Head Coach: Kyle Shanahan
- Quarterback: Jimmy Garoppolo
- Running Back: Raheem Mostert
- Defensive Lineman: Nick Bosa
Giants
- Head Coach: Joe Judge
- Quarterback: Daniel Jones
- Running Back: Saquon Barkley
- Defensive Lineman: Dexter Lawrence
