LANDOVER, Md. -- The San Francisco 49ers square off against the Washington Redskins in Week 6 from FedEx Field. San Francisco is desparate for its first win of the season as Kyle Shanahan, Pierre Garçon and other members of the 49ers return to their old stomping grounds.

Keep it here for highlights, observations and notes throughout Sunday's matchup.

PREGAME

There will be no candy for Reuben Foster in Week 6. The rookie linebacker was listed as questionable but will not play against the Redskins. We will have to wait another week to see Foster's return to game action after suffering a high-ankle sprain in Week 1. That means Brock Coyle will start for the 49ers at MIKE linebacker.

Eric Reid, who was also listed as questionable, is active and will play for the first time since injuring his knee in Week 2. The strong safety is likely to be on a limited snap count as he eases his way back into the lineup.

Cole Hikutini will make his NFL debut after being called up from the practice squad on Saturday.

Here are the rest of San Francisco's inactives: Kendrick Bourne, Dexter McCoil, Kyle Juszczyk, Erik Magnuson, Dekoda Watson and Leon Hall.

And for the Redskins: Rob Kelley, Deshazor Everett, Josh Norman, Josh Harvey- Clemons, Anthony Lanier II, Ty Nsekhe and Jeremy Sprinkle.

Garçon, Logan Paulsen, Aldrick Robinson, DeForest Buckner and Elijah Lee are the 49ers Week 6 captains.

FIRST QUARTER ("--" denotes a new possession)

The 49ers won the toss and elected to defer to the second half.

Jaquiski Tartt started at strong safety for the 49ers. A screen pass from Kirk Cousins to Chris Thompson went for 23 yards and got Washington to San Francisco's 41-yard line. Samaje Perine took another short pass from Cousins for 16 yards to the 49ers 16-yard line.

Cousins found Josh Doctson for an 11-yard touchdown to put Washington up 7-0. (10:14)

That was far too easy as the Redskins effortlessly marched down the field to open the game. The 75-yard scoring drive took just eight plays, and Washington faced just one third down.

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A personal foul for a hit against a defenseless receiver gave the 49ers a free first down near midfield. San Francico couldn't get anything going from there and punted it away to Washington. Hyde's two carries went for -2 yards and Hoyer's lone completion went to George Kittle for just five yards.

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Washington set up from their own 14-yard line. The 49ers forced a much-needed three-and-out.

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The 49ers next drive started with a false start penalty to get them behind the sticks. Hyde's 7-yard run on first down was followed by a Garrett Celek drop and a third-down sack of Hoyer. It wasn't an ideal drive, to say the least, as San Francisco went three-and-out.

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Ahkello Witherspoon entered the game at right cornerback in place of Dontae Johnson. No injury has been reported so it could just be a lineup change. Cousins quickly challenged the rookie with a short pass to Terrelle Pryor Sr. four a 4-yard gain and a first down. Jaquiski Tartt blew up a 3rd-and-1 running play for a loss of one yard to force a Washington punt.

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Washington thought it had a scoop-and-score touchdown on a sack and fumble of Hoyer. The play was reviewed and deemed an incomplete pass as the quarterback's arm was going forward. The game stayed 7-0, Redskins, but San Francisco still went three-and-out.

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A 12-yard pass to Pryor ended the first quarter. San Francisco has mustered just 11 total yards of offense thus far.

SECOND QUARTER

Perine's 8-yard carry got Washington to San Francisco's 44-yard line. Cousins followed with a 4-yard pass to Jamison Crowder to move the chains. Arik Armstead tackled Chris Thompson for a 9-yard loss on a quick toss to the right. The play was blown up from the start, and Thompson kept moving backwards. However, two straight catches by Jordan Reed of 10 and 14 yards got the Redskins another first down to San Francisco's 25.

An offsides penalty moved Washington five yards closer. Thompson followed with an 8-yard carry to the 12-yard line. A 9-yard pass to Reed got the Redskins to the three.

Cousins found Perine for a 3-yard touchdown to put Washington up 14-0. (9:47)

That was a 10-play, 64-yard scoring drive. Cousins now has 121 passing yards and two touchdowns.

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A 21-yard pass to Aldrick Robinson on 3rd-and-10 accounted for the 49ers first third-down conversion of the game. An incompletion and a false start immediately followed San Francisco's first big play. A 7-yard pass to Goodwin on 3rd-and-15 brought back the 49ers punt team. They've been busy today.

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Thompson took a screen pass for 20 yards to open Washington's next possession. Jimmie Ward appeared to have a diving interception, but upon review, it was called an incomplete pass as the ball hit the ground. On the very next play, Cousins' deep pass on third down was intercepted by Rashard Robinson. That's Robinson's first interception of the season.

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Kyle Shanahan has pulled Pierre Garçon. C.J. Beathard entered the game to make his NFL debut. Matt Breida also entered the game and gained 10 yards on his first carry. Beathard's first-career completion went for 13 yards to Celek. On the ensuing third-down, Kittle dropped a pass that would have resulted in a first down. Drops continue to absolutely haunt this 49ers offense. They've had two big ones today.

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Thompson continued to carve up San Francisco's defense. He gained 49-yards on another screen pass. Thompson now has 107 total yards. Solomon Thomas got his second sack of the season on the next play.

Dustin Hopkins' 48-yard field goal made it 17-0, Redskins. (1:51)

Cousins is now up to 201 yards passing, 92 of which have gone to Thompson.

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Goodwin climbed the ladder for a 20-yard leaping grab. Beathard followed with a 30-yard dart down the middle of the field to Kittle. A 12-yard screen pass to Hyde got the 49ers to Washington's 13-yard line. A pass to Garçon gained eight yards to make it 4th-and-2. An unsportsmanlike conduct penalty against Washington set up 1st-and-goal from the 2-yard line. The 49ers were then called for delay of game to move the ball back to the seven. Beathard hit Kittle for a gain of seven yards to the one.

On 4th-and-goal from the 1-yard line, Hyde found the end zone to get San Francisco on the board and cut Washington's lead to 17-7. (0:00)

The 1:51 scoring drive gave the 49ers some life as both teams headed into the locker room for halftime.

THIRD QUARTER

San Francisco got the ball first to open the second half. Hyde gained five yards on his first carry of the third quarter. Beathard's third-down pass to Hyde gained 12 yards and moved the chains. Breida got another first down with a 1-yard run on 3rd-and-inches. Breida then took a short pass for a gain of 11 yards and carried the ball for a gain of 10 to Washington's 30-yard line.

Ryan Kerrigan sacked Beathard on the ensuing first down for a loss of 11 yards. A short pass to Hyde set up a long field-goal attempt for Robbie Gould.

Gould drilled the 52-yarder to make it a one-score game, 17-10. (9:41)

Gould has now made all 15 of his field-goal attempts in 2017 and has 32 consecutive makes dating back to 2015.

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Reid got called for illegal use of hands to give the Redskins a free first down. San Francico got a stop from there as Washington punted it back to the 49ers. Trent Taylor's career long 39-yard punt return gave the 49ers great field position at midfield.

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Raheem Mostert gained 16 yards on 3rd-and-1 to get to Washington's 25-yard line. Beathard took a sack on the next third down, and Gould missed a 47-yard field goal. He pulled it wide to the left to keep the score 17-10, Redskins

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Vernon Davis caught his first pass of the day and fumbled. Jimmie Ward recovered the loose ball and returned it all the way to Washington's 1-yard line.

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Hyde scored his second touchdown of the game on the very next play to tie the game at 17. (3:01)

The running back now has four touchdowns on the season. Gotta love a 1-play, four-second scoring drive.

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Cousins scrambled for 18 yards on Washington's next drive. He then found Ryan Grant for an 18-yard gain on 3rd-and-11 to San Francisco's 40-yard line.

FOURTH QUARTER

Washington opened the final quarter facing 3rd-and-12. The Redskins converted with a 13-yard pass to Thompson, who is now over 100 receiving yards for the game. A 15-yard pass to Grand was followed by an 8-yar pass to Davis.

Solomon Thomas had a huge run stop near the goal line, and Dontae Johnson broke up a third-down pass in the end zone.

Hopkins hit a 21-yard field goal to put the Redskins back on top, 20-17. (10:34)

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Beathard's 11-yard pass to Garçon gave San Francisco a quick first down. His ensuing third-down pass fell incomplete to bring out San Francisco's punt team.

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Davis got free for a 51-yard catch-and-run to the 49ers 22-yard line. Tartt was down briefly after the play before walking to the sideline under his own power. He returned a few plays later. On 3rd-and-5 from the 17, Cousins found Grant for a 7-yard gain. A holding penalty against K'Waun Williams gave the Redskins 1st-and-goal from the 7-yard line.

Cousins took it in himself for a 7-yard touchdown run to make it 26-17 following a missed PAT. (3:28)

It's now a two-score game.

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Beathard's 11-yard pass to Taylor converted on 3rd-and-9. The quarterback then scrambed for 14 yards.

The quarterback then found a wide open Aldrick Robinson for a 45-yard touchdown.

It was Beathard's first-career touchdown.

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Washington recovered the ensuing onside kick, but went three-and-out.

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The 49ers got the ball back at their own 20-yad line with :52 remaining and no timeouts. Beathard found Garçon near the sideline for a quick 22-yard gain. Garçon then caught a tipped pass for a 12-yard gain and fell out of bounds once again. At the Washington 40-yard line, Garçon got called for a mysterious offensive pass interference penalty that moved the 49ers back to midfield.

Beathard's fourth-down pass was intercepted, and the 49ers lost once again. San Francisco is now 0-6 and has lost its last five games by a total of 13 points.