Follow along with 49ers.com for in-game updates, highlights, stats and analysis during the team's Week 3 matchup at Empower Field at Mile High.
Game Information
- San Francisco 49ers vs. Denver Broncos
- Sunday, September 25, 2022
- Empower Field at Mile High
About the Matchup
- Total Matchups: 15
- Series Record: 49ers lead the series 8-7
- 49ers Away Record vs. Broncos: Broncos lead the series 4-2
San Francisco 49ers
Head coach: Kyle Shanahan
Players to watch:
Offense
- FB Kyle Juszczyk
- OL Aaron Banks
- RB Jeff Wilson Jr.
- WR Brandon Aiyuk
Defense
- LB Dre Greenlaw
- CB Charvarius Ward
- S Talanoa Hufanga
- DL Nick Bosa
Denver Broncos
Head Coach: Nathaniel Hackett
Players to watch:
Offense
Defense
- OLB Bradley Chubb
- S Justin Simmons
- S Caden Sterns
- DT D.J. Jones
Week 2 Images
View game photos from the San Francisco 49ers Week 2 matchup vs. the Seattle Seahawks at Levi's® Stadium.

WR Deebo Samuel

QB Trey Lance, RB Jeff Wilson Jr.

49ers Offense

RB Tyrion Davis-Price

LB Azeez Al-Shaair

DL Nick Bosa

LB Oren Burks

QB Trey Lance

LB Fred Warner

WR Brandon Aiyuk

CB Emmanuel Moseley

LB Fred Warner

WR Brandon Aiyuk

S Talanoa Hufanga

WR Jauan Jennings, S George Odum, TE Charlie Woerner

QB Jimmy Garoppolo, FB Kyle Juszczyk

LB Dre Greenlaw

TE Ross Dwelley

49ers Defense

S Talanoa Hufanga

49ers Special Teams

49ers Offense

S Tashaun Gibson Sr.

QB Jimmy Garoppolo

RB Tyrion Davis-Price, TE Ross Dwelley

LB Dre Greenlaw, S Talanoa Hufanga

WR Jauan Jennings

T Trent Williams

RB Jeff Wilson Jr.

TE Ross Dwelley

DL Nick Bosa

FB Kyle Juszczyk

49ers Special Teams

RB Jeff Wilson Jr.

LB Dre Greenlaw

LB Fred Warner

CB Emmanuel Moseley

49ers Defense