The San Francisco 49ers 2020 opponents have been set. Dates and times of the 2020 schedule have yet to be determined, however the 49ers know which teams they will face next season. The official NFL schedule for the upcoming season is likely to be released this coming April.
San Francisco heads into the regular season with the fourth-toughest strength of schedule based on their opponents 2019 win percentages (.527). Only the Miami Dolphins (.529), New York Jets (.533) and New England Patriots (.537) have tougher upcoming schedules. The 49ers are scheduled to play six teams coming off of playoff appearances in 2019.
In addition to San Francisco's divisional opponents (Arizona Cardinals, Los Angeles Rams and Seattle Seahawks), the 49ers will also face the NFC East and AFC East. The 49ers will also see the New Orleans Saints and Green Bay Packers, as both teams also finished first in their respective divisions.
Here's the full list of home and road opponents for the 49ers in 2020.
HOME:
NFC West, Buffalo Bills, Green Bay Packers, Miami Dolphins, Philadelphia Eagles, Washington Redskins
AWAY:
NFC West, Dallas Cowboys, New England Patriots, New Orleans Saints, New York Giants, New York Jets
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Take a look at the locations, coaches and some of the top players for the San Francisco 49ers 2020 opponents.

Week 1 vs. Arizona Cardinals 1:25 p.m. PT (Fox)

Arizona Cardinals head coach Kliff Kingsbury

Arizona Cardinals linebacker Chandler Jones

Week 2 @ New York Jets 10:00 a.m. PT (Fox)

New York Jets head coach Adam Gase

New York Jets quarterback Sam Darnold

New York Jets linebacker C.J. Mosley

Week 3 @ New York Giants 10:00 a.m. PT (Fox)

New York Giants head coach Joe Judge

New York Giants quarterback Daniel Jones

New York Giants defensive lineman Dexter Lawrence

Week 4 vs. Philadelphia Eagles 5:20 p.m. PT (NBC)

Philadelphia Eagles head coach Doug Pederson

Philadelphia Eagles quarterback Carson Wentz

Philadelphia Eagles defensive tackle Fletcher Cox

Week 5 vs. Miami Dolphins 1:05 p.m. PT (Fox)

Miami Dolphins head coach Brian Flores

Miami Dolphins wide receiver DeVante Parker

Miami Dolphins cornerback Xavien Howard

Week 6 vs. Los Angeles Rams 5:20 p.m. PT (NBC)

Los Angeles Rams head coach Sean McVay

Los Angeles Rams quarterback Jared Goff

Week 7 @ New England Patriots 1:25 p.m. PT (CBS)

New England Patriots head coach Bill Belichick

New England Patriots wide receiver Julian Edelman

New England Patriots cornerback Stephon Gilmore

Week 8 @ Seattle Seahawks 1:25 p.m. PT (Fox)

Seattle Seahawks head coach Pete Carroll

Seattle Seahawks linebacker Bobby Wagner

Week 9 vs. Green Bay Packers 5:20 p.m. (Fox/NFL Network/Amazon Prime)

Green Bay Packers head coach Matt LaFleur

Green Bay Packers wide receiver Davante Adams

Green Bay Packers linebacker Za'Darius Smith

Week 10 @ New Orleans Saints 1:25 p.m. PT (Fox)

New Orleans Saints head coach Sean Payton

New Orleans Saints wide receiver Michael Thomas

New Orleans Saints defensive end Cameron Jordan

Week 12 @ Los Angeles Rams 1:05 p.m. PT (Fox)

Los Angeles Rams defensive tackle Aaron Donald

Los Angeles Rams wide receiver Cooper Kupp

Week 13 vs. Buffalo Bills 5:15 p.m. PT (ESPN)

Buffalo Bills head coach Sean McDermott

Buffalo Bills quarterback Josh Allen

Buffalo Bills cornerback Tre'Davious White

Week 14 vs. Washington Football Team 1:25 p.m. (Fox)

Washington Football Team head coach Ron Rivera

Washington Football Team wide receiver Terry McLaurin

Washington Football Team safety Landon Collins

Week 15 @ Dallas Cowboys 5:20 p.m. PT (NBC)

Dallas Cowboys head coach Mike McCarthy

Dallas Cowboys running back Ezekiel Elliott

Dallas Cowboys linebacker Jaylon Smith

Week 16 @ Arizona Cardinals TBD

Arizona Cardinals quarterback Kyler Murray

Arizona Cardinals cornerback Patrick Peterson

Week 17 vs. Seattle Seahawks 1:25 p.m. (Fox)

Seattle Seahawks quarterback Russell Wilson

Seattle Seahawks cornerback Shaquill Griffin